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Double Cycloisomerization as a Novel and Expeditious Route to Tricyclic Heteroaromatic Compounds: Short and Highly Diastereoselective Synthesis of (±)-Tetraponerine T6

[Image: see text] Cu-Assisted double cycloisomerization of bis-alkynylpyrimidines afforded the 5–6–5 tricyclic heteroaromatic skeleton. This transformation was used as a key step in the highly diastereoselective total synthesis of (±)-tetraponerine T6.

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Detalhes bibliográficos
Main Authors: Kim, Joseph T., Gevorgyan, Vladimir
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3687801/
https://ncbi.nlm.nih.gov/pubmed/12489964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol027129t
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