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Serum miR-21 as a Diagnostic and Prognostic Biomarker in Colorectal Cancer

BACKGROUND: The oncogenic microRNAs (miRNAs) miR-21 and miR-31 negatively regulate tumor-suppressor genes. Their potential as serum biomarkers has not been determined in human colorectal cancer (CRC). METHODS: To determine whether miR-21 and miR-31 are secretory miRNAs, we screened expression in med...

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Detalhes bibliográficos
Main Authors: Toiyama, Yuji, Takahashi, Masanobu, Hur, Keun, Nagasaka, Takeshi, Tanaka, Koji, Inoue, Yasuhiro, Kusunoki, Masato, Boland, C. Richard, Goel, Ajay
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3687369/
https://ncbi.nlm.nih.gov/pubmed/23704278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djt101
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