A Role for Fibroblast Growth Factor 19 and Bile Acids in Diabetes Remission After Roux-en-Y Gastric Bypass

OBJECTIVE: Roux-en-Y gastric bypass (RYGB) in humans can remit type 2 diabetes, but the operative mechanism is not completely understood. In mice, fibroblast growth factor (FGF) 15 (FGF19 in humans) regulates hepatic bile acid (BA) production and can also resolve diabetes. In this study, we tested t...

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Main Authors: Gerhard, Glenn S., Styer, Amanda M., Wood, G. Craig, Roesch, Stephen L., Petrick, Anthony T., Gabrielsen, Jon, Strodel, William E., Still, Christopher D., Argyropoulos, George
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2013
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3687273/
https://ncbi.nlm.nih.gov/pubmed/23801799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc12-2255
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