Desmosine-Inspired Cross-Linkers for Hyaluronan Hydrogels

We designed bioinspired cross-linkers based on desmosine, the cross-linker in natural elastin, to prepare hydrogels with thiolated hyaluronic acid. These short, rigid cross-linkers are based on pyridinium salts (as in desmosine) and can connect two polymer backbones. Generally, the obtained semi-syn...

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Detalhes bibliográficos
Main Authors: Hagel, Valentin, Mateescu, Markus, Southan, Alexander, Wegner, Seraphine V., Nuss, Isabell, Haraszti, Tamás, Kleinhans, Claudia, Schuh, Christian, Spatz, Joachim P., Kluger, Petra J., Bach, Monika, Tussetschläger, Stefan, Tovar, Günter E. M., Laschat, Sabine, Boehm, Heike
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3687245/
https://ncbi.nlm.nih.gov/pubmed/23784477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02043
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