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Rapid reversible changes in the rate of histone gene transcription and histone mRNA levels in mouse myeloma cells.

The levels of histone mRNAs are reduced 90 to 95% after treatment of mouse myeloma cells with inhibitors of DNA synthesis which disrupt deoxynucleotide metabolism. In contrast, novobiocin, which inhibits DNA synthesis but does not alter deoxynucleotide metabolism, did not alter histone mRNA levels....

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Detalhes bibliográficos
Main Authors: Graves, R A, Marzluff, W F
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC368702/
https://ncbi.nlm.nih.gov/pubmed/6700595
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