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Pathogenesis of Lassa Fever Virus Infection: I. Susceptibility of Mice to Recombinant Lassa Gp/LCMV Chimeric Virus

Lassa virus (LASV) is a BSL-4 restricted agent. To allow study of infection by LASV under BSL-2 conditions, we generated a recombinant virus in which the LASV glycoprotein (Gp) was placed on the backbone of lymphocytic choriomeningitis virus (LCMV) Cl13 nucleoprotein, Z and polymerase genes (rLCMV C...

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Detalhes bibliográficos
Main Authors: Lee, Andrew M., Cruite, Justin, Welch, Megan J., Sullivan, Brian, Oldstone, Michael B.A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686847/
https://ncbi.nlm.nih.gov/pubmed/23684417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.04.010
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