Toll-like Receptor 1 Polymorphisms and Associated Outcomes in Sepsis Following Traumatic Injury, A Candidate Gene Association Study

OBJECTIVE: To determine if SNPs in TLR1 are associated with mortality, specifically sepsis-associated mortality, in a traumatically injured population. SUMMARY BACKGROUND DATA: Innate immune responses mediated by toll-like receptors (TLRs), induce early inflammatory responses to pathogen and damage-...

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Detalhes bibliográficos
Main Authors: Thompson, Callie M., Holden, Tarah D., Gail, Rona R.N, Laxmanan, Balaji, Black, R. Anthony, O’Keefe, Grant E., Wurfel, Mark M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686843/
https://ncbi.nlm.nih.gov/pubmed/23478521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SLA.0b013e31828538e8
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