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Molecular Pathways: Extracting Medical Knowledge from High Throughput Genomic Data

High-throughput genomic data that measures RNA expression, DNA copy number, mutation status and protein levels provide us with insights into the molecular pathway structure of cancer. Genomic lesions (amplifications, deletions, mutations) and epigenetic modifications disrupt biochemical cellular pat...

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Bibliographic Details
Main Authors: Goldstein, Theodore, Paull, Evan O., Ellis, Matthew J., Stuart, Joshua M.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686839/
https://ncbi.nlm.nih.gov/pubmed/23430023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-2093
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