Clade C HIV-1 isolates circulating in Southern Africa exhibit a greater frequency of dicysteine motif-containing Tat variants than those in Southeast Asia and cause increased neurovirulence

BACKGROUND: HIV-1 Clade C (Subtype C; HIV-1C) is responsible for greater than 50% of infections worldwide. Unlike clade B HIV-1 (Subtype B; HIV-1B), which is known to cause HIV associated dementia (HAD) in approximately 15% to 30% of the infected individuals, HIV-1C has been linked with lower preval...

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Hlavní autoři: Rao, Vasudev R, Neogi, Ujjwal, Talboom, Joshua S, Padilla, Ligia, Rahman, Mustafizur, Fritz-French, Cari, Gonzalez-Ramirez, Sandra, Verma, Anjali, Wood, Charles, Ruprecht, Ruth M, Ranga, Udaykumar, Azim, Tasnim, Joska, John, Eugenin, Eliseo, Shet, Anita, Bimonte-Nelson, Heather, Tyor, William R, Prasad, Vinayaka R
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686704/
https://ncbi.nlm.nih.gov/pubmed/23758766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-61
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