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Placental DNA hypomethylation in association with particulate air pollution in early life

BACKGROUND: There is evidence that altered DNA methylation is an important epigenetic mechanism in prenatal programming and that developmental periods are sensitive to environmental stressors. We hypothesized that exposure to fine particles (PM(2.5)) during pregnancy could influence DNA methylation...

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Autors principals: Janssen, Bram G, Godderis, Lode, Pieters, Nicky, Poels, Katrien, Kiciński, Michał, Cuypers, Ann, Fierens, Frans, Penders, Joris, Plusquin, Michelle, Gyselaers, Wilfried, Nawrot, Tim S
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686623/
https://ncbi.nlm.nih.gov/pubmed/23742113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-8977-10-22
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