BRCA1/2 mutation screening in high-risk breast/ovarian cancer families and sporadic cancer patient surveilling for hidden high-risk families

BACKGROUND: The estimated ratio of hereditary breast/ovarian cancer (HBOC) based on family history is 1.5% in Latvia. This is significantly lower than the European average of 5–10%. Molecular markers like mutations and SNPs can help distinguish HBOC patients in the sporadic breast and ovarian cancer...

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Detalhes bibliográficos
Main Authors: Berzina, Dace, Nakazawa-Miklasevica, Miki, Zestkova, Jekaterina, Aksenoka, Karina, Irmejs, Arvids, Gardovskis, Andris, Kalniete, Dagnija, Gardovskis, Janis, Miklasevics, Edvins
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686592/
https://ncbi.nlm.nih.gov/pubmed/23767878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-14-61
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