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A Novel Bis-Thiourea Organocatalyst for the Asymmetric Aza-Henry Reaction

A novel bis-thiourea BINAM-based catalyst for the asymmetric aza-Henry reaction has been developed. This catalyst promotes the reaction of N-Boc imines with nitroalkanes to afford β-nitroamines with good yields and high enantioselectivities. This catalyst has the advantage that it can be prepared in...

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Autors principals: Rampalakos, Constantinos, Wulff, William D.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686523/
https://ncbi.nlm.nih.gov/pubmed/23795151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adsc.200800214
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