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Mechanical Resistance in Unstructured Proteins
Single-molecule pulling experiments on unstructured proteins linked to neurodegenerative diseases have measured rupture forces comparable to those for stable folded proteins. To investigate the structural mechanisms of this unexpected force resistance, we perform pulling simulations of the amyloid β...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3686333/ https://ncbi.nlm.nih.gov/pubmed/23790381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.05.003 |
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