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Exploiting conformational ensembles in modeling protein-protein interactions on the proteome scale

Cellular functions are performed through protein-protein interactions; therefore, identification of these interactions is crucial for understanding biological processes. Recent studies suggest that knowledge-based approaches are more useful than ‘blind’ docking for modeling at large scales. However,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kuzu, Guray, Gursoy, Attila, Nussinov, Ruth, Keskin, Ozlem
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685852/
https://ncbi.nlm.nih.gov/pubmed/23590674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr400006k
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