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Ameliorative effects of metformin on renal histologic and biochemical alterations of gentamicin-induced renal toxicity in Wistar rats

BACKGROUND: The aim of this study was to test the potential properties of metformin (MF) to protect the kidney from gentamicin (GM)-induced renal toxicity. MATERIALS AND METHODS: In this preclinical study, 50 male Wistar rats were randomly divided into five groups of 10 rats in each. In the first gr...

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Bibliographic Details
Main Authors: Amini, Fatemeh Ghaed, Rafieian-Kopaei, Mahmoud, Nematbakhsh, Mehdi, Baradaran, Azar, Nasri, Hamid
Format: Artigo
Language:Inglês
Published: Medknow Publications & Media Pvt Ltd 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685776/
https://ncbi.nlm.nih.gov/pubmed/23798920
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