Chromosomal alterations associated with overproduction of asparagine synthetase in albizziin-resistant Chinese hamster ovary cells.

The amino acid analog albizziin was used to isolate Chinese hamster ovary cell lines which overproduce asparagine synthetase. Mutants selected in a single step after ethyl methane sulfonate mutagenesis were approximately 10-fold more resistant to the drug than the parental lines and expressed 8- to...

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Εκδόθηκε σε:	Mol Cell Biol
Κύριοι συγγραφείς:	Andrulis, I L, Duff, C, Evans-Blackler, S, Worton, R, Siminovitch, L
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Taylor & Francis 1983
Θέματα:	Research Article
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC368547/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6133214/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.3.3.391-398.1983
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