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Exosomes isolated from mycobacteria-infected mice or cultured macrophages can recruit and activate immune cells in vitro and in vivo

Over 2 billion people are infected with M. tuberculosis (M.tb); however, only 5–10% of those infected will develop active disease. Recent data suggest that containment is controlled locally at the level of the granuloma and that granuloma architecture may differ even within a single infected individ...

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Detalhes bibliográficos
Main Authors: Singh, Prachi P., Smith, Victoria L., Karakousis, Petros C., Schorey, Jeffery S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685416/
https://ncbi.nlm.nih.gov/pubmed/22723519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103638
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