Intracellular translocation and differential accumulation of cell-penetrating peptides in bovine spermatozoa: evaluation of efficient delivery vectors that do not compromise human sperm motility

STUDY QUESTION: Do cell penetrating peptides (CPPs) translocate into spermatozoa and, if so, could they be utilized to deliver a much larger protein cargo? SUMMARY ANSWER: Chemically diverse polycationic CPPs rapidly and efficiently translocate into spermatozoa. They exhibit differential accumulatio...

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Bibliografiske detaljer
Main Authors: Jones, Sarah, Lukanowska, Monika, Suhorutsenko, Julia, Oxenham, Senga, Barratt, Christopher, Publicover, Steven, Copolovici, Dana Maria, Langel, Ülo, Howl, John
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685333/
https://ncbi.nlm.nih.gov/pubmed/23585561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humrep/det064
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