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Unexpected clinical sequelae of Gitelman syndrome: hypertension in adulthood is common and females have higher potassium requirements

BACKGROUND: Gitelman syndrome (GS) is a rare inherited disorder caused by mutations in SLC12A3, encoding the thiazide-sensitive transporter NCCT (sodium chloride co-transporter) in the distal tubule. It is characterized by renal potassium (K) and magnesium (Mg) wasting, relative hypotension and hypo...

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Bibliografiske detaljer
Main Authors: Berry, Miriam R., Robinson, Caroline, Karet Frankl, Fiona E.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685308/
https://ncbi.nlm.nih.gov/pubmed/23328711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfs600
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