Alternative TEL-JAK2 fusions associated with T-cell acute lymphoblastic leukemia and atypical chronic myelogenous leukemia dissected in zebrafish

BACKGROUND: Chromosomal translocations resulting in alternative fusions of the human TEL (ETV6) and JAK2 genes have been observed in cases of acute lymphoblastic leukemia and chronic myelogenous leukemia, but a full understanding of their role in disease etiology has remained elusive. In this study...

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Huvudupphovsmän: Onnebo, Sara M. N., Rasighaemi, Parisa, Kumar, Janani, Liongue, Clifford, Ward, Alister C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Ferrata Storti Foundation 2012
Ämnen:
Molecular & Cellular Basis of Acute Leukemia
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685286/
https://ncbi.nlm.nih.gov/pubmed/22733019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.064659
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