Use of CBL exon 8 and 9 mutations in diagnosis of myeloproliferative neoplasms and myelodysplastic/myeloproliferative disorders: an analysis of 636 cases

We analyzed 636 patients with diverse myeloproliferative neoplasms or myelodysplastic/myeloproliferative neoplasms for mutations of the Casitas B-cell lymphoma gene (CBL(mut)) in exons 8 and 9 and performed correlations to other genetic alterations. CBL(mut) were detected in 63 of 636 (9.9%) of thes...

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Hlavní autoři: Schnittger, Susanne, Bacher, Ulrike, Alpermann, Tamara, Reiter, Andreas, Ulke, Madlen, Dicker, Frank, Eder, Christiane, Kohlmann, Alexander, Grossmann, Vera, Kowarsch, Andreas, Kern, Wolfgang, Haferlach, Claudia, Haferlach, Torsten
Médium: Artigo
Jazyk:Inglês
Vydáno: Ferrata Storti Foundation 2012
Témata:
Chronic Myeloproliferative Disorders
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685285/
https://ncbi.nlm.nih.gov/pubmed/22733026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.065375
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