Factor VIII and von Willebrand factor are ligands for the carbohydrate-receptor Siglec-5

BACKGROUND: Factor VIII (FVIII) and von Willebrand factor (VWF) circulate in plasma in a tight non-covalent complex, being critical to hemostasis. Although structurally unrelated, both share the presence of sialylated glycan-structures, making them potential ligands for sialic-acid-binding-immunoglo...

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Dettagli Bibliografici
Autori principali: Pegon, Julie N., Kurdi, Mohamad, Casari, Caterina, Odouard, Soline, Denis, Cécile V., Christophe, Olivier D., Lenting, Peter J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ferrata Storti Foundation 2012
Soggetti:
Original Articles and Brief Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685284/
https://ncbi.nlm.nih.gov/pubmed/22733016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.063297
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