Mutational analysis of simian virus 40 T antigen: stimulation of cellular DNA synthesis and activation of rRNA genes by mutants with deletions in the T-antigen gene.

The biological activity of several deletion mutants of simian virus 40, cloned in pBR322, was determined. Three functions of the simian virus 40 A gene were studied: (i) the ability to express T antigen; (ii) the ability to induce cell DNA replication; and (iii) the ability to reactivate silent rRNA...

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Hauptverfasser: Soprano, K J, Galanti, N, Jonak, G J, McKercher, S, Pipas, J M, Peden, K W, Baserga, R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1983
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC368524/
https://ncbi.nlm.nih.gov/pubmed/6300657
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