Interferon-β Therapy Prolongs Survival in Rhesus Macaque Models of Ebola and Marburg Hemorrhagic Fever

There is a clear need for novel, effective therapeutic approaches to hemorrhagic fever due to filoviruses. Ebola virus hemorrhagic fever is associated with robust interferon (IFN)–α production, with plasma concentrations of IFN-α that greatly (60- to 100-fold) exceed those seen in other viral infect...

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Autori principali: Smith, Lauren M., Hensley, Lisa E., Geisbert, Thomas W., Johnson, Joshua, Stossel, Andrea, Honko, Anna, Yen, Judy Y., Geisbert, Joan, Paragas, Jason, Fritz, Elizabeth, Olinger, Gene, Young, Howard A., Rubins, Kathleen H., Karp, Christopher L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2013
Soggetti:
Major Articles and Brief Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685222/
https://ncbi.nlm.nih.gov/pubmed/23255566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis921
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