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COMPARATIVE PHARMACOKINETICS OF PAMAM-OH DENDRIMERS AND HPMA COPOLYMERS IN OVARIAN-TUMOR-BEARING MICE

The purpose of this study was to model data from a head to head comparison of the in vivo fate of hyper-branched PAMAM dendrimers with linear HPMA copolymers in order to understand the influence of molecular weight (MW), hydrodynamic size (Rh) and polymer architecture on biodistribution in tumor-bea...

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Bibliographic Details
Main Authors: Sadekar, S., Linares, O., Noh, GJ., Hubbard, D., Ray, A., Janát-Amsbury, M., Peterson, C. M., Facelli, J., Ghandehari, H.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685189/
https://ncbi.nlm.nih.gov/pubmed/23795337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13346-012-0119-6
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