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Disruption of Transient Receptor Potential Canonical Channel 1 Causes Incomplete Cytokinesis and Slows the Growth of Human Malignant Gliomas

Despite decades of research, primary brain tumors, gliomas, lack effective treatment options and present a huge clinical challenge. Particularly, the most malignant subtype, Glioblastoma multiforme, proliferates extensively and cells often undergo incomplete cell divisions, resulting in multinucleat...

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Main Authors: BOMBEN, VALERIE C., SONTHEIMER, HARALD
Formato: Artigo
Idioma:Inglês
Publicado: 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685186/
https://ncbi.nlm.nih.gov/pubmed/20544850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.20994
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