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Supramolecular Filaments Containing a Fixed 41% Paclitaxel Loading

We report here the self-assembly of a rationally designed paclitaxel drug amphiphile into well-defined supramolecular filaments that possess a fixed 41% paclitaxel loading. These filaments can exert effective cytotoxicity against a number of cell lines comparable to that of free paclitaxel.

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Detalhes bibliográficos
Main Authors: Lin, Ran, Cheetham, Andrew G., Zhang, Pengcheng, Lin, Yi-an, Cui, Honggang
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685178/
https://ncbi.nlm.nih.gov/pubmed/23612448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cc41896k
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