Nitric-Oxide Synthase Knockout Modulates Ca(2+)-Sensing Receptor Expression and Signaling in Mouse Mesenteric Arteries

Extracellular calcium (Ca(2+)(e))-induced relaxation of isolated, phenylephrine (PE)-contracted mesenteric arteries is dependent on an intact perivascular sensory nerve network that expresses the Ca(2+)-sensing receptor (CaSR). Activation of the receptor stimulates an endocannabinoid vasodilator pat...

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Hlavní autoři: Awumey, Emmanuel M., Bridges, Lakeesha E., Williams, Cicely L., Diz, Debra I.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2013
Témata:
Cardiovascular
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684838/
https://ncbi.nlm.nih.gov/pubmed/23639802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.113.205534
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