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The membrane-topogenic vectorial behaviour of Nrf1 controls its post-translational modification and transactivation activity
The integral membrane-bound Nrf1 transcription factor fulfils important functions in maintaining cellular homeostasis and organ integrity, but how it is controlled vectorially is unknown. Herein, creative use of Gal4-based reporter assays with protease protection assays (GRAPPA), and double fluoresc...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3684815/ https://ncbi.nlm.nih.gov/pubmed/23774320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02006 |
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