MTHFR C677T and A1298C variant genotypes and the risk of microsatellite instability among Iranian colorectal cancer patients

Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in the folate metabolic pathway. We aimed to test the hypothesis that C677T and A1298C variants of MTHFR predispose to microsatellite instable (MSI) colorectal cancer. We determined MTHFR genotypes in 175 sporadic colorectal cancer patients...

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Autori principali: Naghibalhossaini, Fakhraddin, Mokarram, Pooneh, Khalili, Islam, Vasei, Mohammad, Hosseini, Seyed Vahid, Ashktorab, Hassan, Rasti, Mozhgan, Abdollahi, Kourosh
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684801/
https://ncbi.nlm.nih.gov/pubmed/20193847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cancergencyto.2009.11.014
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