MTHFR C677T and A1298C variant genotypes and the risk of microsatellite instability among Iranian colorectal cancer patients

Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in the folate metabolic pathway. We aimed to test the hypothesis that C677T and A1298C variants of MTHFR predispose to microsatellite instable (MSI) colorectal cancer. We determined MTHFR genotypes in 175 sporadic colorectal cancer patients...

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Hauptverfasser: Naghibalhossaini, Fakhraddin, Mokarram, Pooneh, Khalili, Islam, Vasei, Mohammad, Hosseini, Seyed Vahid, Ashktorab, Hassan, Rasti, Mozhgan, Abdollahi, Kourosh
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684801/
https://ncbi.nlm.nih.gov/pubmed/20193847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cancergencyto.2009.11.014
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