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Detection of cancer before distant metastasis

BACKGROUND: To establish a distant metastasis (DM) cells must disseminate from the primary tumor and overcome a series of obstacles, the metastatic cascade. In this study we develop a mathematical model for this cascade to estimate the tumor size and the circulating tumor cell (CTC) load before the...

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Autors principals: Coumans, Frank AW, Siesling, Sabine, Terstappen, Leon WMM
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684526/
https://ncbi.nlm.nih.gov/pubmed/23763955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-283
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