Flt3 ligand expands CD103(+) dendritic cells, FoxP3(+) T regulatory cells and attenuates Crohn’s-like murine ileitis

BACKGROUND: Imprinting an effector or regulatory phenotype on naïve T cells requires education at induction sites by dendritic cells (DC). In the current studies we analyzed the effect of inflammation on the frequency of mononuclear phagocytes (MP) and the effect of altering their frequency by admin...

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Autori principali: Collins, Colm B., Aherne, Carol M., McNamee, Eóin N., Lebsack, Matthew D. P., Eltzschig, Holger, Jedlicka, Paul, Rivera-Nieves, Jesús
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684390/
https://ncbi.nlm.nih.gov/pubmed/22068168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2011-300820
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