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TET2 promotes histone O-GlcNAcylation during gene transcription

TET enzymes including TET1, 2 and 3 convert 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC)(1) and regulate gene transcription(2-5). However, this molecular mechanism by which TET family enzymes regulate gene transcription remains elusive(5-6). Here, using protein affinity purification, we...

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Detaylı Bibliyografya
Asıl Yazarlar: Chen, Qiang, Chen, Yibin, Bian, Chunjing, Fujiki, Ryoji, Yu, Xiaochun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684361/
https://ncbi.nlm.nih.gov/pubmed/23222540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11742
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