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Insights into the iron-ome and manganese-ome of Δmtm1 Saccharomyces cerevisiae Mitochondria

Biophysical spectroscopies and LC-ICP-MS were used to evaluate the iron-ome and manganese-ome of mitochondria from Δmtm1 yeast cells. Deleting the mitochondrial carrier gene MTM1 causes Fe to accumulate in mitochondria and Mn superoxide dismutase (SOD2) activity to decline. One explanation for this...

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Main Authors: Park, Jinkyu, McCormick, Sean P., Chakrabarti, Mrinmoy, Lindahl, Paul A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684240/
https://ncbi.nlm.nih.gov/pubmed/23598994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3mt00041a
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