Heritability Estimates Identify a Substantial Genetic Contribution to Risk and Outcome of Intracerebral Hemorrhage

BACKGROUND AND PURPOSE: Previous studies suggest that genetic variation plays a substantial role in occurrence and evolution of intracerebral hemorrhage (ICH). Genetic contribution to disease can be determined by calculating heritability using family-based data, but such an approach is impractical f...

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Hlavní autoři: Devan, William J., Falcone, Guido J., Anderson, Christopher D., Jagiella, Jeremiasz M., Schmidt, Helena, Hansen, Björn M., Jimenez-Conde, Jordi, Giralt-Steinhauer, Eva, Cuadrado-Godia, Elisa, Soriano, Carolina, Ayres, Alison M., Schwab, Kristin, Kassis, Sylvia Baedorf, Valant, Valerie, Pera, Joanna, Urbanik, Andrzej, Viswanathan, Anand, Rost, Natalia S., Goldstein, Joshua N., Freudenberger, Paul, Stögerer, Eva-Maria, Norrving, Bo, Tirschwell, David L., Selim, Magdy, Brown, Devin L., Silliman, Scott L., Worrall, Bradford B., Meschia, James F., Kidwell, Chelsea S., Montaner, Joan, Fernandez-Cadenas, Israel, Delgado, Pilar, Greenberg, Steven M., Roquer, Jaume, Lindgren, Arne, Slowik, Agnieszka, Schmidt, Reinhold, Woo, Daniel, Rosand, Jonathan, Biffi, Alessandro
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684199/
https://ncbi.nlm.nih.gov/pubmed/23559261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.111.000089
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