APOE Genotype Predicts Extent of Bleeding and Outcome in Lobar Intracerebral Hemorrhage

BACKGROUND: APOE alleles ε2/ε4 increase risk of intracerebral hemorrhage (ICH) in the lobar regions, presumably through their influence on risk of cerebral amyloid angiopathy. We investigated whether these variants also associate with ICH severity, specifically larger ICH volume at presentation. MET...

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Main Authors: Biffi, Alessandro, Anderson, Christopher D., Jagiella, Jeremiasz M., Schmidt, Helena, Kissela, Brett, Hansen, Björn M., Jimenez-Conde, Jordi, Pires, Caroline R., Ayres, Alison M., Schwab, Kristin, Cortellini, Lynelle, Pera, Joanna, Urbanik, Andrzej, Romero, Javier M., Rost, Natalia S., Goldstein, Joshua N., Viswanathan, Anand, Pichler, Alexander, Enzinger, Christian, Rabionet, Raquel, Norrving, Bo, Tirschwell, David L., Selim, Magdy, Brown, Devin L., Silliman, Scott L., Worrall, Bradford B., Meschia, James F., Kidwell, Chelsea S., Broderick, Joseph P., Greenberg, Steven M., Roquer, Jaume, Lindgren, Arne, Slowik, Agnieszka, Schmidt, Reinhold, Woo, Daniel, Rosand, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153411/
https://ncbi.nlm.nih.gov/pubmed/21741316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1474-4422(11)70148-X
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