l-Alanine Auxotrophy of Lactobacillus johnsonii as Demonstrated by Physiological, Genomic, and Gene Complementation Approaches

Using a chemically defined medium without l-alanine, Lactobacillus johnsonii was demonstrated to be strictly auxotrophic for that amino acid. A comparative genetic analysis showed that all known genes involved in l-alanine biosynthesis are absent from the genome of L. johnsonii. This auxotrophy was...

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Bibliografske podrobnosti
izdano v:Appl Environ Microbiol
Main Authors: van der Kaaij, Hengameh, Desiere, Frank, Mollet, Beat, Germond, Jacques-Edouard
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2004
Teme:
Genetics and Molecular Biology
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC368417/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15006820/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.70.3.1869-1873.2004
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