Activation of Protease-Activated Receptor 2-Mediated Signaling by Mast Cell Tryptase Modulates Cytokine Production in Primary Cultured Astrocytes

Protease-activated receptor 2 (PAR-2), which is abundantly expressed in astrocytes, is known to play major roles in brain inflammation. However, the influence of the natural agonist of PAR-2, tryptase, on proinflammatory mediator releasedfrom astrocytes remains uninvestigated. In the present study,...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Zeng, Xiaoning, Zhang, Shu, Xu, Luwei, Yang, Haiwei, He, Shaoheng
التنسيق: Artigo
اللغة:Inglês
منشور في: Hindawi Publishing Corporation 2013
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684029/
https://ncbi.nlm.nih.gov/pubmed/23818741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/140812
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