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Structural Refinement from Restrained-Ensemble Simulations Based on EPR/DEER Data: Application to T4 Lysozyme

DEER (Double Electron Electron Resonance) is a powerful pulsed ESR (electron spin resonance) technique allowing the determination of distance histograms between pairs of nitroxide spin-labels linked to a protein in a native-like solution environment. However, exploiting the huge amount of informatio...

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Bibliographic Details
Main Authors: Islam, Shahidul M., Stein, Richard A., Mchaourab, Hassane, Roux, Benoît
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684008/
https://ncbi.nlm.nih.gov/pubmed/23510103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp311723a
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