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Polyelectrolyte Multilayers Promote Stent-Mediated Delivery of DNA to Vascular Tissue

We report an approach to deliver DNA to vascular tissue in vivo using intravascular stents coated with degradable, DNA-containing polyelectrolyte multilayers (PEMs). Ionically-crosslinked multilayers ~120 nm thick were fabricated layer-by-layer on the surfaces of balloon-mounted stainless steel sten...

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Detalhes bibliográficos
Main Authors: Saurer, Eric M., Jewell, Christopher M., Roenneburg, Drew A., Bechler, Shane L., Torrealba, Jose R., Hacker, Timothy A., Lynn, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683994/
https://ncbi.nlm.nih.gov/pubmed/23597075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm4005222
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