Subcellular Profiling Reveals Distinct and Developmentally Regulated Repertoire of Growth Cone mRNAs

Cue-directed axon guidance depends partly on local translation in growth cones. Many mRNA transcripts are known to reside in developing axons, yet little is known about their subcellular distribution or, specifically, which transcripts are in growth cones. Here laser capture microdissection (LCM) wa...

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Autors principals: Zivraj, Krishna H., Tung, Yi Chun Loraine, Piper, Michael, Gumy, Laura, Fawcett, James W., Yeo, Giles S. H., Holt, Christine E.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2010
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683943/
https://ncbi.nlm.nih.gov/pubmed/21084603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1800-10.2010
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