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The role of DNA mismatch repair in generating genetic diversity and drug resistance in malaria parasites

Although the mechanisms by which malaria parasites develop resistance to drugs are unclear, current knowledge suggests a main mechanism of resistance is the alteration of target enzymes by point mutation. In other organisms, defects in DNA mismatch repair have been linked to increased mutation rates...

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Detalhes bibliográficos
Main Authors: Bethke, Lara, Thomas, Susan, Walker, Kerone, Lakhia, Ronak, Rangarajan, Radha, Wirth, Dyann
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683857/
https://ncbi.nlm.nih.gov/pubmed/17583362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2007.05.003
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