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HDAC7 Inhibits Osteoclastogenesis by Reversing RANKL-Triggered β-Catenin Switch
The bone-resorbing osteoclast is essential for skeletal remodeling, yet its deregulation contributes to diseases such as osteoporosis and cancer bone metastasis. Here we identify histone deacetylase 7 (HDAC7) as a key negative regulator of osteoclastogenesis and bone resorption using both in vitro c...
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| Hoofdauteurs: | , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Endocrine Society
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3683803/ https://ncbi.nlm.nih.gov/pubmed/23204328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1302 |
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