Epithelial neoplasia in Drosophila entails switch to primitive cell states

Only select cell types in an organ display neoplasia when targeted oncogenically. How developmental lineage hierarchies of these cells prefigure their neoplastic propensities is not yet well-understood. Here we show that neoplastic Drosophila epithelial cells reverse their developmental commitments...

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Detalhes bibliográficos
Main Authors: Khan, Sumbul J., Bajpai, Anjali, Alam, Mohammad Atif, Gupta, Ram P., Harsh, Sneh, Pandey, Ravi K., Goel-Bhattacharya, Surbhi, Nigam, Aditi, Mishra, Arati, Sinha, Pradip
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683752/
https://ncbi.nlm.nih.gov/pubmed/23708122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1212513110
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