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Pirin is an iron-dependent redox regulator of NF-κB

Pirin is a nuclear nonheme Fe protein of unknown function present in all human tissues. Here we describe that pirin may act as a redox sensor for the nuclear factor κB (NF-κB) transcription factor, a critical mediator of intracellular signaling that has been linked to cellular responses to proinflam...

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Detalhes bibliográficos
Main Authors: Liu, Fange, Rehmani, Imran, Esaki, Shingo, Fu, Rong, Chen, Lirong, de Serrano, Vesna, Liu, Aimin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683729/
https://ncbi.nlm.nih.gov/pubmed/23716661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1221743110
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