Circadian patterns of gene expression in the human brain and disruption in major depressive disorder

A cardinal symptom of major depressive disorder (MDD) is the disruption of circadian patterns. However, to date, there is no direct evidence of circadian clock dysregulation in the brains of patients who have MDD. Circadian rhythmicity of gene expression has been observed in animals and peripheral h...

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Hlavní autoři: Li, Jun Z., Bunney, Blynn G., Meng, Fan, Hagenauer, Megan H., Walsh, David M., Vawter, Marquis P., Evans, Simon J., Choudary, Prabhakara V., Cartagena, Preston, Barchas, Jack D., Schatzberg, Alan F., Jones, Edward G., Myers, Richard M., Watson, Stanley J., Akil, Huda, Bunney, William E.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683716/
https://ncbi.nlm.nih.gov/pubmed/23671070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1305814110
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