Antibodies targeting dengue virus envelope domain III are not required for serotype-specific protection or prevention of enhancement in vivo

The envelope (E) protein of dengue virus (DENV) is composed of three domains (EDI, EDII, EDIII) and is the main target of neutralizing antibodies. Many monoclonal antibodies that bind EDIII strongly neutralize DENV. However in vitro studies indicate that anti-EDIII antibodies contribute little to th...

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Detaylı Bibliyografya
Asıl Yazarlar: Williams, Katherine L., Wahala, Wahala M.P.B., Orozco, Susana, de Silva, Aravinda M., Harris, Eva
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683589/
https://ncbi.nlm.nih.gov/pubmed/22537810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.03.003
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