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In Vivo Optical Molecular Imaging of Matrix Metalloproteinase Activity Following Celecoxib Therapy for Colorectal Cancer
We present an optical molecular imaging approach to measure the efficacy of the COX-2 inhibitor celecoxib on tumor growth rate through its effect on MMP activity. A xenograft model of colorectal cancer was generated in nude mice, which were then randomized to receive celecoxib vs vehicle. MMP activi...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3683544/ https://ncbi.nlm.nih.gov/pubmed/22954186 |
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