Association between common alcohol dehydrogenase gene (ADH) variants and schizophrenia and autism

Humans express at least seven alcohol dehydrogenase (ADH) isoforms that are encoded by ADH gene cluster (ADH7–ADH1C–ADH1B–ADH1A–ADH6–ADH4–ADH5) at chromosome 4. ADHs are key catabolic enzymes for retinol and ethanol. The functional ADH variants (mostly rare) have been implicated in alcoholism risk....

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Main Authors: Zuo, Lingjun, Wang, Kesheng, Zhang, Xiang-Yang, Pan, Xinghua, Wang, Guilin, Tan, Yunlong, Zhong, Chunlong, Krystal, John H., State, Matthew, Zhang, Heping, Luo, Xingguang
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683370/
https://ncbi.nlm.nih.gov/pubmed/23468174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-013-1277-4
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