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Nicotine, Through Upregulating Pro-Survival Signaling, Cooperates with NNK to Promote Transformation

Cigarette smoking is a mixture of thousands of compounds, many of which are carcinogens, such as NNK [4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone]. Nicotine, as an addictive substance in cigarette, has been shown to promote growth of non-neuronal cells. It is unclear how nicotine cooperates with...

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Bibliographic Details
Main Authors: Nishioka, Takashi, Guo, Jinjin, Yamamoto, Daisuke, Chen, Lihua, Huppi, Petra, Chen, Chang Yan
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683296/
https://ncbi.nlm.nih.gov/pubmed/19911375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22392
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